In a majority of pathologies and/or surgical procedures, a shift occurs in the hemostasis balance between the prothrombotic and hemorrhagic states, and identifying and monitoring the shift between the two states is important under all these conditions. Furthermore, in some circumstances, being able to control the degree of shift can make a critical difference in outcome -- for example, consider the case of using artificial surface devices, where it is beneficial to keep the patient in a slightly anti-coagulated state.

We provide links here to selected application areas with clinical examples, and for each we:

  • explain why the shifts occur
  • illustrate the shifts in hemostasis
  • show how the TEG® Hemostasis Analyzer detects each of the hemostatic states and identifies the degree of imbalance present.

Armed with this information, and using the TEG-guided Hemostasis and Blood Management strategy, clinicians can make better diagnostic and therapeutic decisions.

The following schematic shows a representative tracing obtained from the TEGŪ hemostasis analyzer. It shows both coagulation and fibrinolysis as it occurs in a whole blood sample. The schematic is labeled with the test names that the TEGŪ analyzer reports, and links the test names to the major physiological component being evaluated. For a comprehensive look at the TEGŪ technology and sample results, click here.

 
R Time to initial fibrin formation
Angle Clot strengthening, rapidity of fibrin-buildup

MA

 

G

Clot strength, represents maximum dynamics of fibrin and platelet bonding
CI Linear coagulation index using above parameters
LY30 Rate of clot breakdown

 

Each TEGŪ sample produces numeric and graphical results, and both can be used to assist in diagnosis. Note that the TEGŪ software also provides computer-assisted diagnostic tools that use both the numeric and graphical results in suggesting an interpretation of any present coagulopathy. Many graphical patterns are suggestive of a coagulopathy, and a quick visual inspection can provide a great deal of insight. Examples of these are found in the sections dealing with clinical applications.

For a review of the various patterns that are seen in TEGŪ tracings, click here.

For a discussion of the TEG-guided Hemostasis and Blood Management guidelines, click here.

Coronary Artery Bypass Graft (CABG)
Liver transplantation
Exposure to artificial surface devices (ASD)
Percutaneous Coronary Angioplasty (PTCA)
Disseminated Intravascular Coagulation (DIC)

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